Help Sick Little Sis

[Cyber F] Modification Academy - Doctor's Alter Ego [ENG]

(C37) [Little Mermaid Henshuubu (Various)] LITTL MREMAID SELLECT (Urusei Yatsura, Maison Ikkoku)

(C74) [Kaitoushinshidan (Kaishinshi)] Wafuwafuwide (Little Busters!)

(C94) [Little Hamlet (Kiira)] Hatoba Tsugu no Kono Ko ni Shimashita (Hatoba Tsugu) [Chinese] [homolive汉化组]

Gakkou de Nakadashi no Shukudai ga Deta node Onii-chan ni Tetsudatte morau Hon | Book where my school sent me nakadashi homework so I got help from oniichan

(Reitaisai 9) [Little Hamlet (Ra Kii)] Komeiji Satori no Soushitsu (Touhou Project)

[Shinobu Tanei] Little Stepsister Fantasy Virgin Ch. 1-3 [English] {Tadanohito}

(Fueta Kishi) My Little Sister Came!(Comic X-EROS 2013-09)[ENG][The Lusty Lady Project]

[Hara] Akazukin-chan

[Porori] My First Time is with.... My Little Sister?! (Ongoing)

(C65) [Mubimuchuu, Little Kinetic (Yukishiro Yoshi, Morino Usagi)] sLAVER

[Pecan (Makunouchi)] Tamakeri Akazukin

[mmm] Yuagari Imouto Onaho | After-Bath Little-Sister Sex-Sleeve (Comic LO 2017-11) [English] {Mistvern} [Digital]

(C88) (Little★Cosmos [Ayano Rumi]) Netorare Princess Lucina (Fire Emblem Awakening)

[Misagi Nagomu] The little sister bank Ch.1-3

[Salad] Uchi no Imouto | My Little Sister (Show Bitch) [English] {5 a.m.}

Fat sister

(C89) [65535th Avenue. (Akahito)] Makoto Shower (Tokyo 7th Sisters)

Pictures of Sis [English] [Rewrite] [EZ Rewriter]

[Mimoton] Natsu Basu (Little Busters)

(C86) [AKA-MISO (Mamemu)] Natsu Dashi Umi Demo Itte Ichaicha Shitara ii ja Nai! | Nothing Wrong with a Little Summer Fun at the Beach! (Neon Genesis Evangelion) [English] {Spluuuuurt}

[Smokin' Sick Style (Rokumonsen Kako)] And I'm Home (Puella Magi Madoka Magica) [English]

(Reitaisai 13) [Little☆Hamlet (Kiira~)] Komeiji Satori no Nichijou (Touhou Project) [Chinese] [灵梦书院汉化]

[Yaminabe] Uchi no Imouto ga Yuusha ni Mezameta Ken ni Tsuite | The Case When My Little Sister Became the Hero (Loring Holiday) [English] [BlindEye]

Kyonyuu no Onee-chan wa Suki desu ka? FÜNF | Do You Like Big Sis' Big Tits? FÜNF

Imouto wa Amma Ama | My Little Sister Is So Gentle!

[Porori] My First Time is with.... My Little Sister?! Ch.12

(C84) [Little☆Hamlet (Lu☆cky)] Kokoro no Kokoro (Touhou Project)

(C84) [Hamanasu Chaya (Hamanasu)] B=Witch! (Little Witch Academia) [English] [Risette]

[Little mantis (Kuloamaki)] Nioi Sumire [Digital]

[Little mantis (Kuloamaki)] Seku Pure!!! ~Sexual Predators~

(C79) [Shinohara Heavy Industry (Various)] sis-con 5 (Ore no Imouto ga Konna ni Kawaii Wake ga Nai)

Imouto Pantsu (Little Sister's Panties) [English]

[Union of the Snake (Shinda Mane)] Psychosomatic Counterfeit EX- A.J. in E.G. Style (Ver. 02) (My Little Pony: Friendship Is Magic)

Big Sister Little Sister After

(COMITIA122) [squeezecandyheaven (Ichihaya)] Imouto wa Mistress (Ge) | My Little Sister Is My Mistress <Final Chapter> [English] [ATF]

(C84) [Little☆Hamlet (Ra Kii)] Kokoro no Kokoro (Touhou Project) [English] {Hennojin}

(C59) [Studio BIG-X (Arino Hiroshi)] Mousou Mini Theater 6 (Cardcaptor Sakura, Sister Princess)

[Rico] Imouto Mama | Little-Sister Mama (Onii-chan Asobo) [English] {Mistvern}

[Little mantis (Kuloamaki)] Seku Pure!!!3 ~Sexual Predators~ [English] [obsoletezero]

Omae Mada Imouto o Onaho ni Shite Nee no? | Are You Still Not Using Your Little Sister As An Onahole?

[Zaki Zaraki] Uchi no Imouto ga Warito Kawaii | My Little Sister Is Relatively Cute (Hamezukids) [English] {Mistvern}

(C54) [Cu-little2 (Beti, MAGI)] Cu-Little Onemunya~ (The Last Blade)

[Tiger] Yuuwaku・Imouto #2 Onii-chan wa seishori gakari | Little Sister Temptation #2 Onii-chan is in Charge of My Libido Management (COMIC Reboot Vol. 07) [English] [Digital]

[Porori] My First Time is with.... My Little Sister?! Ch.06

Imouto wa Juken ni Ochita | My little sister failed her entrance exam.

[Fumihiko] Sis Bro (COMIC Megastore 2012-08)

[St. Rio (Naoki, Purin)] Ore no Imouto to Sono Onna Tomodachi ga Ero Kawaii Wake ga Nai | My Little Sister and Her Friend Can't Be This Ero-Cute (Ore no Imouto ga Konna ni Kawaii Wake ga Nai) [English] {doujin-moe.us} [Digital]

(C61) [Cu-little2 (Betty, MAGI)] Cu-Little Pokontsunya~ (Various)

Tensei Akazukin wa Jinrou ni Kyouai Sareru | 转生小红帽被狼人疯狂疼爱

[JACK-POT (Jyura)] RAIN -Kokuhaku shite Kita no wa Imouto datta- | RAIN -It Was My Sister Who Confessed to Me- [English] [Nisor] [Digital]

(C89) [Takanaedoko (Takanae Kyourin)] Imouto no Otetsudai 6 | Little Sister Helper 6 [English] {Hennojin}

[Little mantis (Kuloamaki)] PEKEPEKE [Chinese] [臭鼬娘漢化組]

[Shinobu Tanei] Imouto Shojo Gensou | Little Stepsister Fantasy Virgin [English] {Tadanohito}

(COMITIA114) ["Tsu" ga Mittsu. (Tsuttsu)] Sis-Nyou! [Chinese] [无毒汉化组]

[Happongi Hills (SIS)] Bunny Christmas ~Shinmai Otokonoko Santa no Okurimono~ [English]

[Little mantis (Kuloamaki)] pekepeke

[ro] Ookami to Akazukin Ch. 3 (Monthly QooPA 2014-11) [Chinese] [落莲汉化组] [Digital]

[Little Mermaid Henshuubu (Various)] Kacchuu Densetsu (Urusei Yatsura)

Imouto no Betatsuku Hada to Sono Kusai | My Little Sister's Sticky Body and Odor

Can't Help It [English] [Rewrite] [olddog51]

[Little mantis (Kuloamaki)] Kichiku Iinchou Hayana-sama wa... - Satanic class president Hayana is...

[Shinobu Tanei] Little Stepsister Love Space Ch. 1-10 [English] {Tadanohito}

KISS X SIS

[Raijinkai (Haruki Genia)] Oreimo Binetsu Tyuihou 3 | Little Sister Fever Warning 3 (Ore no Imouto ga Konna ni Kawaii Wake ga Nai) [English] =LWB=

(C84) [keepON (Hano Haruka)] Sister Complex! (Little Busters!)

Help Me, Sis [English] [Rewrite]

Imouto wa Taiyo deshita. | My little sister is the sun.

[Shinobu Tanei] Imouto Netsuai Ryouiki | Little Stepsister Love Space [English] {Tadanohito}

[Shinobu Tanei] Imouto Shojo Gensou | Little Stepsister Fantasy Virgin Ch. 1-9 [English] {Tadanohito}

[Zat] Twi to Shimmer no Ero Manga | The Manga In Which Sunset Shimmer Takes A Piss (My Little Pony: Friendship is Magic) [English]

(C84) [Sexual Khorosho (Lasto)] Omoi Kitte Imoto to Onnayu ni Haitte Mita | I went to the women's bath with my little sister [English] [ATF]

Sick SIblings [English] [Rewrite] [EZ Rewriter]

(Reitaisai 14) [Little Hamlet (Kiira)] Komeiji Satori no Psychometry (Touhou Project)

(C81) [Sniff Dogs (Ujiie Moku)] Imouto-tachi wa Oshiri ga Setsunai | My Little Sister's Ass is Demanding (Boku wa Tomodachi ga Sukunai) [English] [DMD]

[Shinobu Tanei] Little Stepsister Love Space Ch. 1-11 [English] {Tadanohito}

(C88) [Little Hamlet (Kiira)] Komeiji Satori no Elevator wa Toilet ja arimasen (Touhou Project)

[Orenjiya (Orenji)] Mushroom Fever (Little Witch Academia) [English] [Digital]

(C68) [Applecat (Potekoro)] Little My Sister (Makai Tenshi Djibril)

Bon Appetite!

(CR29) [Studio BIG-X (Arino Hiroshi)] Mousou Mini Theater 7 (Cardcaptor Sakura, Sister Princess)

Tsubasa × Help

[Kotobuki Kazuki] Sis Ero Ch. 1-7 [English] {Tadanohito}

[ro] Ookami to Akazukin Ch. 3 (Monthly QooPA 2014-11) [Digital]

(C79) [Little☆Hamlet × Nymphet (Lu☆cky)] Kichiku Ou Reimu - Touhou Koumakyou Kouryakubon -Ike Mawari Hen- (Touhou Project) [English] =Koudesu + Super Shanko&LS=

[Saegusa Kohaku] Imouto Fushin or...!? | Little Sister Insincerity or...!? (Comic Megastore 2010-12) [ENG] [Yoroshii]

Imouto wa Sickness no Omake | My Little Sister is Sickly: Extra Story

Letter About Sis [English] [Rewrite] [olddog51]

(C94) [Little Hamlet (Kiira)] Hatoba Tsugu no Kono Ko ni Shimashita | Hatoba Tsugu Became My Daughter (Hatoba Tsugu) [English] [DKKMD Translations]

(COMIC1☆2) [Himawari-Noren (Chihiro Aoi)] Sai Nounin Ouenka (Kiss x Sis)

[Cu-little2 (Betty, MAGI)] Cu-Little Mint-chan Nya~ (DEWPRISM / Threads Of Fate)

[Himeshibori (YAMATO)] Sasami ga Oshikko o Gaman Shite Omorashi Suru Hon (Little Busters!) [Digital]

Yuu Nee no Otsukai | Big-Sis Yuu's Errand

[ro] Ookami to Akazukin Ch. 2 (Monthly QooPA 2014-09) [Chinese] [E个人汉化] [Digital]

[Breakrabbit] Little witch love (Little Witch Academia) (English) [Hououin Kyouma]

[Porori] My First Time is with.... My Little Sister?! Ch.04

Giving Sis Her Medicine [English] [Rewrite] [EZ Rewriter]

[System Speculation (Imai Youki)] LITTLE ANGEL (Neon Genesis Evangelion)

[BeNantoka] Maji Love Imouto | Seriously LOVE Little Sister (Comic LO 2015-07) [English] {5 a.m.}

(C83) [bocchi koubou (rutubo)] Kudo no Shikkin Hon (Little Busters!)

[TSF no F (NOMU)] Succubus Club e Youkoso ~Imouto no Imouto ni Sareta Ore~ | Welcome to the Succubus Sorority ~Turning into my younger sister's little sister~ [English]

(C92) [DAICHIBOKUJOU (Makiba)] xxx (Little Witch Academia) [Chinese] [无毒汉化组]

Imouto Comp | little sister complex

(C99) [Little Hamlet (Kiira)] Ikigao Miraretai Mi-ya-chan

[Juna Juna Juice] Mukatsuku Imouto wa Chanto Shikaranakucha 1~5 Matome | Annoying Little Sister needs to be Scolded [English] [NovaScans]

[Takitomo Tsuguo] Itsudemo Honban!

Koakuma Switch - Little Diabolic Girl Switch

Knocking Up Sis [English] [Rewrite] [olddog51]

[Porori] My First Time is with.... My Little Sister?! Ch.02

Kyonyuu no Onee-chan wa Suki desu ka? | Do you like Big Sis' Big Tits?

(C84) [CassiS (RIOKO)] Hoshizukiyo (FInal Fantasy XIII-2)

[SISAchi (Shisachi)] Imouto ga Nikka de Ani to Ecchi suru Hanashi

(C94) [Little Hopper with H (Hashibiro Kou)] Rachirare Shoujo wa, Manga no Naka de __. Koharu Hen

[Mizu] Sharing the Blame ~In any case, I love my little sister~ [English] {5 a.m.}

(C90) [Fuyunonchi (Fuyuno Mikan)] Little Sister With Grande Everyday

(SC48) [R-WORKS (ROS)] Mikuni-san-chi no Miharu-san (Kiss x Sis) [English] {Hennojin}

(C85) [Kurimomo (Tsukako)] Kirakira Boshi | Twinkle Star (Little Busters!) [English] [SAI-subs]

[Arsenal] Imouto no Sukinamono | What His Little Sister Likes (COMIC Penguin Club 2012-08 Vol.312) [English] {desudesu} [Digital]

Sister Cleaire No Seiso To Yokubou

[Shinobu Tanei] Little Stepsister Love Space Ch. 1-6 [English] {Tadanohito}

[Chan Shiden] Can't My Little Sister Be My Girlfriend? (COMIC LO 2019-01) [English] [Digital] [Learn JP with H]

[Little mantis (Kuloamaki)] pekepeke [English]

[Magukappu (Magukappu)] DIACO (Little Witch Academia)

[URAN] Imouto wa Kohaku Iro | Little Sister Is Amber (Comic Penguin Club 2008-12) [ENG] [Yoroshii]

Imouto wa Amnesia close | My Little Sister Has Amnesia - close

[Little mantis (Kuloamaki)] Nioi Sumire 2 [Digital]

(Reitaisai 9) [Little Hamlet (Ra Kii)] Komeiji Satori no Soushitsu (Touhou Project) [English]

Imouto Bloomer Ch. 2 | Little Sister Bloomers

[Orenjiya (Orenji)] Movie Night (Little Witch Academia) [Chinese] [沒有漢化] [Digital]

[Shinobu Tanei] Little Stepsister Fantasy Virgin Ch. 1 [English] {Tadanohito}

[Porori] My First Time is with.... My Little Sister?! (Ch.41 - 45)[English](Ongoing)

My Big 'n' Sexy Little Sis

(COMIC1☆7) [Takanaedoko (Takanae Kyourin)] Imouto no Otetsudai 4 | Little Sister Helper 4 [English] {Hennojin}

(C80) [Haisui no Jin (Naruko)] Nanikore?! (Little Busters!)

[Marii-Pily] lAnako og 6 (Little Witch Academia)

(C49) [STUDIO UNBALANCE (Various)] Sadistic Angels (Neon Genesis Evangelion)

[Caramel Dow] Little Sister Rex 2 [ENG]

(C73) [Shunka Shuutou (Amano Chiharu)] Wanko no Jikan (Little Busters!)

[Haine Club (Umino Haine)] LITTLE FRAGRANCE PREMIUM (Sister Princess)

(COMIC1☆3) [Upagoya (Endori)] Riko-nee to Asobo (Kiss x Sis)

[Kaneko Ken] Onee-chan ni yoru Shinsei Houkei Chiryou | The True Phimosis Treatment by Sis [English]